18: Albert Wesker

PROJECT: NEW DAWN HISTORY
Having successfully acquired Umbrella’s assets after the trial in which the Umbrella Corporation was convicted and found guilty (In in RE:UC), he collected his resources an d moved headquarters to New Your city where the busy workings of every day antics successfully hid his whereabouts form the authorities so he was found innocent of all charges and further pardoned by the US government after standing witness against Umbrella and Oswald E. Spencer. His interest in resurrecting Umbrella has only intensified and he is dedicated to raising an empire from the ashes; a dream that is beginning to take flight into reality.
After acquiring Sherry and being given legal custody he moved them to his New York facility though he still continued his work, Wesker raised Sherry as his own, being familiar to her as her father’s long time friend. They had an Uncle/Niece relationship though it has evolved over the years to a Father/Daughter situation.
Upon gathering his various samples, and getting a hold of the forgotten Antarctica base, he opened a large science department dedicated to studying, refining, and continuing work on the samples. Also housed in the building is the multilayer SANCTUM complex which functions as a containment and rehabilitation community for the various Tyrants acquired. For example, the body of Steve Burnside (RE:CV) was brought to SANCTUM and is housed there. Tyrants are offered living space and should they retain their humanoid form and consciousness, are admitted to the tyrant community - offered assistance and support to better control themselves and their abilities. An ability ‘cap’ is placed on each tyrant to help maintain mental stability and prevent mutation. The degrees of a ‘cap’ vary depending on the individual.
The body of William Birkin was also recovered after having been taken captive by Umbrella after the events of RE:2 in an abandoned facility where he was imprisoned by Morpheus D. Duvall and in one last act of mutinous jealousy took a sample of the active G-Virus for his own manipulation.
The long time friend, rivals, and lovers were reunited. William was also introduced into the SANCTUM program though by request he resides on a private above ground level he shares with Wesker and Steve (who has by this time become a top agent and something of a trophy wife) and is now the head researcher for P:ND under Wesker’s direction.
Wesker’s vision has continued to materialize and knowing this, he has turned his attention to his main goal. Finding and eliminating Las Plagas from the planet as they serve only to complicate his master vision. Las Plagas’s involvement with Umbrella is great as it is speculated that one of their own (Spencer) was most likely a top-ranking Master Plaga (A ‘Sovereign’). This only fuels Wesker’s determination to rid the planet of these alien creatures.
Project: New Dawn was specifically developed to produce more able Tyrants to dispatch and destroy Las Plagas.


IN GAME HISTORY
All information from Wikipedia

Resident Evil Zero
Resident Evil Zero depicts Wesker's actions the day before the events of the "Mansion Incident", serving as a behind-the-scenes co-conspirator with William Birkin. Zero also expands on Wesker's past as an Umbrella trainee and his role in the assassination of Umbrella co-founder Dr. James Marcus.

Resident Evil (original and remake)
Albert Wesker first appeared as one of the three major supporting characters in the original Resident Evil and the only one to appear in both of the main characters' (Chris Redfield and Jill Valentine) scenarios. He is presented as the cool and collected leader of Alpha Team who remains calm in the face of danger as he and the survivors head into the Spencer Estate. However, he disappears early in the game and only makes sporadic appearances through the course of the story. Later in the game, Wesker's true identity and agenda are uncovered: he is a former Umbrella researcher and an Umbrella operative within the Raccoon Police Department. Wesker is following Umbrella's orders to use the S.T.A.R.S. as test subjects against the various mutant creatures and bio-organic weapons (BOWs) infesting the mansion. However, near the game's end, Wesker implies that he has his own plans and is in fact double-crossing Umbrella. He also blackmails Alpha team member Barry Burton into assisting him by threatening his family; Wesker claims that if he is killed by Barry, or Barry refuses to assist him, an Umbrella team stationed outside Burton's residence will storm inside his house and kill his wife and two daughters.

Albert Wesker in Resident Evil Zero and the Gamecube Resident Evil remake.
At the end of the game, Wesker is killed by Tyrant in the mansion's underground lab created by Umbrella workers. Wesker's death varies between ending: in Chris' ending (as well as in versions of Jill's ending where Barry dies), Wesker unleashes the Tyrant from its containment capsule, only to be impaled by the creature's claw. In the better versions of Jill's ending, Wesker runs off into the lab's control room and activates the self-destruct mechanism only to be killed. When the player enters the control room, they will find Wesker's corpse next to the control panel with a Chimera in the area (this scenario only takes place in the original game). Wesker's role in the 2002 GameCube remake of the game remains essentially identical to the original version, although one of the endings was revised so that Wesker apparently escapes from the mansion alive. It is later revealed that William Birkin provided him with an experimental virus, which he injects himself before freeing the Tyrant. He allows the Tyrant to "kill" him, knowing that the virus will revive him and endow him with superhuman strength and agility.

Resident Evil Code: Veronica
Despite his "death", Wesker returns in Resident Evil Code: Veronica. No longer working for Umbrella, Wesker is now an operative of the same mysterious, unnamed "organization" which employs Ada Wong, seeking to steal Umbrella's research. Wesker is shown to have gained superhuman strength and agility, but at the expense of his humanity. Wesker's sunglasses are knocked off during a fist-fight with Chris Redfield, revealing his mutated cat-like eyes. CODE: Veronica X, an extended version of the game, splices ten minutes of additional cut scenes into the main story (including an extended ending), all involving Wesker himself and adding further plot depth. In the extended ending, he tells Chris and Claire Redfield that he retrieved Steve Burnside's body after his death because his remains still contained the T-Veronica virus. Wesker taunts Claire, saying that Steve may yet be revived. Also, during his final fight with Chris, Wesker's face is badly burned by an explosion which separates the two, forcing them to withdraw from their battle and escape the facility. However, in Wesker's next appearance six years later in Resident Evil 4, his face appears undamaged.
Wesker's Report, a fictional documentary narrated by Wesker, is a promotional DVD that was originally sold with CODE: Veronica X. The report is a retelling of the first three Resident Evil games from Wesker's point-of-view. Wesker's Report also retcons Wesker's death to explain his presence in CODE: Veronica. Wesker reveals that he was betraying both the S.T.A.R.S. and Umbrella during the first game, as he had secretly switched his allegiance to one of Umbrella's rival companies. Wesker's new employers asked him to supply them with the Tyrant's "combat data". Before his final confrontation with the surviving S.T.A.R.S. members in the Arklay Research Facility's lab, Wesker injected himself with a new type of serum provided by his former lab partner William Birkin. Wesker in fact intended for the Tyrant to slay him, setting the stage for his revival. However, he'd also assumed that by the time the serum resurrected him, the Tyrant would have killed the remaining S.T.A.R.S., thereby allowing Wesker to collect the Tyrant's combat data. The S.T.A.R.S. unwittingly foiled Wesker's plan by killing the Tyrant. Without the combat data, Wesker lost face with his new employers, thus solidifying his hatred of the surviving S.T.A.R.S. (Chris in particular). The report also reveals that Wesker's new employers are the same as Ada's. Wesker helped her from behind-the-scenes during the events of Resident Evil 2 and rescued Ada from Raccoon City before its final destruction. Wesker's Report I also reveals that Wesker has custody of Birkin's daughter Sherry.
Another fictional documentary, Wesker's Report II, was published online through Capcom's official websites during the release of the GameCube remake of the original game. This documentary features excerpts of Wesker's journals sent to Ada, detailing his career as a researcher in the Arklay Research Facility. The journal also describes the origins of every viral agent introduced in the series up to that point and details the horrible experiments to which Lisa Trevor (a mutated girl featured in Resident Evil Remake) was subjected. The journals also expand on Wesker's relationship with Birkin, revealing that they were best friends as well as rivals.

Resident Evil: The Umbrella Chronicles
In addition to narrating the story itself, Wesker played the central role in Resident Evil: The Umbrella Chronicles,[5] and was, for the first time in the series, canon as a playable character. Wesker's chapters are unique, and expand upon his role in the storyline. The three chapters dedicated to him are "Beginnings", "Rebirth", and "Dark Legacy".
Beginnings: Having failed to reclaim the Umbrella Training Facility (Resident Evil Zero) due to Dr. Marcus' attack, Wesker must escape from the facility in order to pursue his next mission - luring the S.T.A.R.S. team to the Spencer Mansion. After successfully reaching the surface, he is met by Sergei Vladimir, who dispatches an "Ivan" Tyrant to punish him for his failure.

Rebirth: Wesker awakes inside the Spencer Mansion, resurrected by William Birkin's experimental virus after having allowed the Tyrant to kill him. Since the virus inside him has mutated, he has gained superhuman strength with no negative side effects (aside from his abnormal eyes). (The effects are first shown in the fight with the 2 Ivans, however effects of super-human strength have been shown, e.g. when he killed a large Chimera with a single kick or when he thrust punches a zombie if it grapples him.) He discovers that the Tyrant has been destroyed and that the mansion is about to explode. Furthermore he finds that all the research data in the lab has been stolen by Sergei Vladimir, and that his access privileges have been revoked by the Red Queen. With minutes to spare, Wesker fights his way out of the mansion, demonstrating the awesome powers granted by the virus. At the very end he finds the exit blocked by his onetime test subject, the nearly immortal Lisa Trevor, and the two engage in one last epic showdown.
Death's Door: While not a playable character in this scenario, Wesker does make an appearance giving orders to Ada Wong via video-phone during the Raccoon City outbreak. He provides her with information (and her grappling hook gun) that saves her life, and guides her escape so that she can bring him the G-Virus sample taken from William Birkin's dead body.
Dark Legacy: In the year 2003, Wesker manipulates Jill Valentine and Chris Redfield in order to get them to attack a facility belonging to Umbrella, their common enemy. Wesker infiltrates the facility, where Sergei Vladimir had unleashed the T-Virus in order to deal with the intrusion. Sergei soon confronts Wesker, and sends two of his Ivan Tyrants to kill him. Wesker proves to be more than a match for the Ivans thanks to his superhuman abilities, and continues his penetration of the facility. At the end Wesker faces Sergei for the last time, and Sergei injects himself with a virus that mutates him into a monster. The two old enemies clash, with Wesker prevailing again,

allowing Wesker to steal all the data Umbrella accumulated over years of research. This data is established as the key to reviving the Umbrella Corporation, which is exactly what Wesker plans to do in Resident Evil 4.
During and after the credits, more about Wesker is revealed. It is stated that the Umbrella Corporation was finally found guilty on all charges of its involvement in the Raccoon City outbreak, due to evidence that Wesker provided from the stolen data. As a key witness, Wesker also implicated Ozwell E. Spencer personally, starting a global manhunt for the Umbrella founder. At the very end of the game, Wesker is shown entering the same command room that he uses in Resident Evil 4. He places all of the stolen Umbrella data into his computer, allowing him to take possession of all the company's assets and information, and promises that he will meet Spencer again and usher in a new era for himself.
Though The Umbrella Chronicles marks Wesker's first appearance as a playable character in the main storyline, he has previously been playable in some of the non-plot minigames in the series. These include the "Battle Game" in CODE: Veronica and "The Mercenaries" in Resident Evil 4. He was also playable in the multiplayer modes featured in Resident Evil: Deadly Silence (the Nintendo DS port of the first game). Additionally, the Sega Saturn version of Resident Evil features a zombiefied version of Wesker as an enemy in the Saturn-exclusive "Battle Mode" minigame, although this minigame precedes Wesker's revival in Code: Veronica.

Resident Evil 4
Wesker appears in the "Assignment Ada" minigame, as well as in the "Separate Ways" scenario in the PS2 and Wii versions, directing Ada from the command room he acquired in Resident Evil: The Umbrella Chronicles. Both scenarios depict Wesker's ongoing efforts to revive the Umbrella Corporation under his leadership, using Ada Wong and Jack Krauser as his covert agents. He instructs Ada to retrieve a Plagas sample from Saddler. Although Ada is successful in retrieving the sample of a Master Plaga, she gives Wesker a false sample. The "Ada's Report" documentary, also included in the PS2, PC, and Wii versions of the "Separate Ways" scenario, describes Wesker's character and intentions from Ada's perspective.
He is also a playable character in "The Mercenaries" minigame.